2008-11-13

QianYongJian, and other three U.S. scientists discovered and as a result of the development of the green fluorescent protein and was the prize

Osamu Shimomura

Martin Chalfie

Roger Y. Tsien (QianYongjian) A Beijing at 5:45 p.m. on October 8, 2008 Nobel Prize in Chemistry announced that the United States Woods Hole Marine Biological Laboratory Osamu Shimomura (the village under repair), Columbia University Martin Chalfie and the University of California, San Diego's Roger Y. Tsien (QianYongjian, the QianXueSheng 's niece), three U.S. scientists, and found that as a result of the development of a green fluorescent protein (GFP) and to receive the Award. Before the award was forecast to become a reality.

This year's Nobel Prize in Chemistry Award for the original discovery of GFP, as well as a series of important developments have been marked as a tool to use in the biological sciences. Through DNA technology, researchers will now be able to GFP and other interesting but not visible protein linked. Light-emitting tags so that scientists can observe the movement of the protein, as well as the location of the interaction.

Green fluorescent protein in 1962 for the first time in Aequorea victoria jellyfish were observed. Since then, it has become a modern biological science and one of the most important tool. GFP in with the help of researchers has developed a number of ways to observe the previously invisible in the process, such as brain cell development and proliferation of cancer cells how to proceed.

Tens of thousands of different types of protein found in the living organism, an important chemical process control of the tiny details. If the protein machinery malfunction, disease will follow. That is why the biological sciences so eager to portray a different protein in the body.

GFP in with the help of researchers can study a variety of tracking the fate of cells, such as Alzheimer's disease in the nerve cells of the injury, or an embryo's development is the pancreas, how to create insulin-producing ¦Â cells. In a unique study, scientists used a variety of colors mark the success of the mouse brain in different nerve cells.

The three scientists were awarded the contributions are as follows:

Village for the first time under repair from Aequorea victoria (west coast of North America with a current drift of jellyfish) isolated GFP. He found that the protein will be issued under ultraviolet light bright green.

Martin Chalfie demonstrated GFP as a variety of biological phenomena of light-emitting the value of genetic markers. In an initial experiment, he used to make GFP Caenorhabditis elegans 6 separate cell with color.

QianYongjian is a major contribution to make people understand the issue of GFP fluorescence mechanism. At the same time, he expanded beyond the green tags can be used with other colors, so that scientists can impose a variety of proteins and cells of a different color. All this, so that at the same time tracking a number of different biological processes to become a reality.

Osamu Shimomura, 1928 was born in Kyoto, Japan, and in 1960 received a doctorate in Organic Chemistry University in Nagoya, Japan, the United States Woods Hole Marine Biological Laboratory (MBL) and Boston University School of Medicine, honorary professor of retirement. Martin Chalfie, 1947 was born, grew up in Chicago in the United States, the United States in 1977 to obtain a doctorate in neurobiology at Harvard University, in 1982, he was appointed professor of biology at Columbia University. Roger Y. Tsien, 1952 was born in New York, in 1977 the British doctorate in physiology at the University of Cambridge, the United States in 1989, he was appointed professor at the University of California, San Diego.

It is learned that the three will split the prize money of SEK 10,000,000.

Author: RenXiaoPeng MeiJing

Source: Science Times NEWSPAPER 08th/October/2008